Patient Zero, previously known as Patient Z, is an upcoming American-British fantasy-horror thriller film directed by Stefan Ruzowitzky and written by Mike Le. The film stars Matt Smith, Natalie Dormer, Stanley Tucci and Clive Standen. Filming began on March 3, 2015 in London. Screen Gems will release the film sometime in 2017.
After a pandemic outbreak, a mutated form of rabies results in most humans being turned into a highly intelligent new species known as “The Infected”: a human survivor, Morgan (Matt Smith), with the ability to talk with the “infected,” investigates these species and pursues “Patient Zero” to find an antidote to save humanity, including his infected wife. Aiding Morgan on the mission to find Patient Zero is CDC virologist Dr. Gina Rose (Natalie Dormer), leading the scientific research efforts, while Colonel Knox (Clive Standen) is in charge of the military front.
The script for the movie was the subject of a bidding war between different several studios including Fox Searchlight Pictures. Silver Pictures, Davis Entertainment, Broken Road Productions, Donners’ Company, Vincent Newman Entertainment and Misher Films. The script is set in a post-apocalyptic world, about a man who has to find an antidote for his zombie infected wife. Screen Gems eventually won the bidding war and Vincent Newman was set to produce through his Vincent Newman Entertainment. Austrian director Stefan Ruzowitzky was set to direct the film on May 2, 2014.